COVID-19 infection fatality rate in community-dwelling elderly
Updated: Apr 20
By: Stanford's Dr. John Ioannidis
Comorbidities and other conditions [Summary of data as of 1/9/2022]
"Table 3 shows the types of health conditions and contributing causes mentioned in conjunction with deaths involving coronavirus disease 2019 (COVID-19). The number of deaths that mention one or more of the conditions indicated is shown for all deaths involving COVID-19 and by age groups. For over 5% of these deaths, COVID-19 was the only cause mentioned on the death certificate. For deaths with conditions or causes in addition to COVID-19 [about 95% of deaths] , on average, there were 4.0 additional conditions or causes per death." [Emphasis added]
From the abstract of Infection fatality rate of COVID-19 in community-dwelling populations with emphasis on the elderly: An overview":
"Results: Twenty-five seroprevalence surveys representing 14 countries were included. Across all countries, the median IFR in community-dwelling elderly and elderly overall was 2.9% (range 0.2%- 6.9%) and 4.9% (range 0.2%-16.8%) without accounting for seroreversion (2.4% and 4.0%, respectively, accounting for 5% monthly seroreversion). Multiple sensitivity analyses yielded similar results. IFR was higher with larger proportions of people >85 years. Younger age strata had low IFR values (median 0.0013%, 0.0088%, 0.021%, 0.042%, 0.14%, and 0.65%, at 0-19, 20-29, 30-39, 40- 49, 50-59, and 60-69 years even without accounting for seroreversion).
Conclusions: The IFR of COVID-19 in community-dwelling elderly people is lower than previously reported. Very low IFRs were confirmed in the youngest populations."